Controlled aggregation of methylene blue in silica–methylene blue nanocomposite for enhanced 1O2 generation

Organic photosensitizers can facilitate photochemical singlet-oxygen ( 1 O 2 ) production, providing a promising strategy for photocatalysis, photodynamic therapy, and environmental protection. Unfortunately, most organic tend to self-aggregate because of their hydrophobicity conjugated ?–? electronic structure, leading the inactivation photosensitizing capabilities. Thus, controlled aggregation is critical photosensitizer’s applications. We report nanocomposite porous silica nanoaggregates photosensitizer methylene blue (P-SiO x NAs/MB) that allows control (MB). This nanocomposite-photosensitizer consists highly dispersed MB in P-SiO NAs enhances production under light irradiation without ability MB. The enhanced generation rate NAs/MB 1.36 times larger than free behavior contrasted with MB-encapsulated organo-silica nanoparticles, due self-aggregation within particles. study provides creating an efficient via suppression enhance .